石河子大學(xué)藥學(xué)院導(dǎo)師：鄭秋生

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石河子大學(xué)藥學(xué)院導(dǎo)師：鄭秋生

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石河子大學(xué)藥學(xué)院導(dǎo)師：鄭秋生 正文

[導(dǎo)師姓名]
鄭秋生

[所屬院校]
石河子大學(xué)

[基本信息]
導(dǎo)師姓名：鄭秋生
性別：男
人氣指數(shù)：2108
所屬院校：石河子大學(xué)
所屬院系：藥學(xué)院
職稱：教授
導(dǎo)師類型：
招生專業(yè)：藥學(xué)、作物學(xué)
研究領(lǐng)域：藥學(xué)；中藥學(xué)、



[通訊方式]
電子郵件：30843985@qq.com

[個人簡述]
鄭秋生，1967年10月生，山東壽光人，北京大學(xué)博士后，教授。2006年入選教育部新世紀優(yōu)秀人才?，F(xiàn)任濱州醫(yī)學(xué)院中西醫(yī)結(jié)合學(xué)院院長，新疆特種植物藥資源教育部重點實驗室主任，蘭州大學(xué)兼職教授、中國海洋大學(xué)教兼職教授，石河子大學(xué)特聘教授。醫(yī)藥領(lǐng)域國家科技重大專項“十二五”計劃技術(shù)管理專家，國家科技獎勵評審專家，國家“863”計劃專家?guī)斐蓡T，國家學(xué)位和研究生教育專家組成員，西北天然藥物(中藏藥)產(chǎn)業(yè)技術(shù)創(chuàng)新戰(zhàn)略聯(lián)盟專家技術(shù)委員會委員。山東省、河北省、重慶市以及上海市科技獎勵和科技計劃的評審專家。曾主持或參與國家“863”、“973”、國家自然科學(xué)基金等重大研究項目三十余項，先后參與十多個新藥開發(fā)項目的藥效學(xué)評價研究工作，其中已申報并批準臨床新藥9項，待申報或批準臨床達10多項，申請相關(guān)專利多項。在國內(nèi)外學(xué)術(shù)期刊發(fā)表論文200余篇，其中SCI、EI收錄論文100余篇，出版專著5 部，獲得省部級科技進步一等獎2項，二等獎5項?，F(xiàn)為多家國際學(xué)術(shù)期刊編委、約稿人或特邀審稿人。
對口支援西部高校工作十周年突出貢獻個人

[科研工作]
1. 異甘草素調(diào)控糖代謝誘導(dǎo)黑色素瘤細胞凋亡機制研究，，國家自然科學(xué)基金（項目編號31471338）90萬元，主持人鄭秋生，2015.01-2018.12
2. 甘草查爾酮A 誘導(dǎo)膀胱癌T24 細胞凋亡機制研究，國家自然科學(xué)基金（項目編號81260338）55萬元，主持人鄭秋生，2012-2016；
3. 光果甘草中三種化合物聯(lián)合分離新技術(shù)研發(fā)及中試（13C26216516410），科技型中小企業(yè)創(chuàng)業(yè)投資引導(dǎo)基金，80萬元，主持人鄭秋生，2014.1-2016.12
4. 新疆獨特生境下植物次生多酚類產(chǎn)物的抗腫瘤活性研究，兵團杰出青年基金（項目編號2011CD006）,30萬元，主持人鄭秋生，2011-2013。
5. 異甘草素誘導(dǎo)HL-60細胞分化機制的研究，國際科技合作計劃（2012BC001），13萬元，主持人鄭秋生，2012-2014；
6. 異甘草素誘導(dǎo)腫瘤細胞從分化到凋亡過程中氧化還原調(diào)控機制研究，973計劃前期研究專項（2010CB535003），2009-2012主持人，70萬元
7. NADPH氧化酶在異甘草素誘導(dǎo)HL-60細胞分化中的作用研究，國家自然科學(xué)基金（項目編號30960451），主持人，22萬，2010-2012
8. 化藥一類抗腫瘤新藥維泰醇及維泰醇類化合物成藥性研究，科技部重大新藥創(chuàng)制科技重大專項（2009ZX09103-141），428.61萬元，主持人，2009-2012
9. 活性氧在阿片代謝過程中產(chǎn)生機制及其對阿片受體結(jié)合能力的影響 國家自然科學(xué)基金（項目編號30860074），主持人，25萬元2009-2011
10. 抗肝纖維化復(fù)方新藥甘草紫參片的研究與開發(fā) 國家“十一五”支撐計劃 主持人 2007-2009 (2006BAI06A18-22) 180萬元
藥學(xué)；藥理學(xué)
Current Biochemistry Research編委
SM Journal of Carcinogenesis& Mutagenesis, 編委
Journal of Pharmaceutical Research編委
Journalof Clinical Breast Cancer Research.編委
The Open Bioactive Compound Journal.
Annals of Urological Research, Editorial Board forAnnals of Urological Research,
American Journal of Laboratory Medicine, Editorial Member.
American Journal of Leukemia Research
Journal of Chemistry（ Guest Edit a Special Issue）主編
SRL Urology 編委
Global Journal of Advanced Radiation Research 共同主編
Jacobs Journal of Drug Metabolism and Toxicology （編委）
The Editorial Board of Chinese Journal of Biology 編委
International Journal of Pharmaceutical Sciences and Developmental Research編委
The member of The Society for Free Radical Research會員
世界中醫(yī)藥學(xué)會網(wǎng)絡(luò)藥理學(xué)專業(yè)委員會副會長；
中華預(yù)防醫(yī)學(xué)會自由基預(yù)防醫(yī)學(xué)專業(yè)委員會理事，中國藥理學(xué)會會員；
山東省心功能研究會健康與養(yǎng)生專業(yè)委員會副主任委員；
醫(yī)藥領(lǐng)域國家科技重大專項“十二五”計劃技術(shù)管理專家，
國家科技獎勵評審專家，國家“863”計劃專家?guī)斐蓡T，
國家學(xué)位和研究生教育專家組成員，
西北天然藥物(中藏藥)產(chǎn)業(yè)技術(shù)創(chuàng)新戰(zhàn)略聯(lián)盟專家技術(shù)委員會委員
新疆特種植物藥資源教育部重點實驗室主任、學(xué)術(shù)委員會副主任
1. Dan Wang, Chendong Yang, Zhuien Wang, Yi Yang, Defang Li, Xiaojie Ding, Wenjuan Xu, Qiusheng Zheng. Norcantharidin combined with Coix seed oil synergistically induces apoptosis and inhibits hepatocellular carcinoma growth by downregulating regulatory T cells accumulation. Scientific Reports 7, Article number: 9373 (2017), doi:10.1038/s41598-017-09668-2
2. Dong Wang, Xinjie Zhang, Defang Li, Wenjin Hao, Fanqing Meng, Bo Wang, Jichun Han, and Qiusheng Zheng. Kaempferide Protects against Myocardial Ischemia/Reperfusion Injury through Activation of the PI3K/Akt/GSK-3β Pathway. Mediators of Inflammation,2017, Article ID 5278218
3. Dan Wang, Wenjuan Xu, Xiaoyu Chen, Jichun Han, Lina Yu, Caixia Gao, Wenjin Hao, Xiaona Liu, Qiusheng Zheng and Defang Li. Icariin induces cell differentiation and cell cycle arrest in mouse melanoma B16 cells via Erk1/2-p38-JNK-dependent pathway. Oncotarget, Advance Publications 2017
4. Jichun Han, Dong Wang, Defang Li, Xiaoyu Chen, Bo Wang, Fenghua Wang, Xixona Liu, Jing Shang and Qiusheng Zheng. Licochalcone E protects against carbon tetrachloride?induced liver toxicity by activating peroxisome proliferator-activated receptor gamma. MOLECULAR MEDICINE REPORTS. July 28, 2017, DOI: 10.3892/mmr.2017.7268
5. Han J, Wang D, Ye L, Li P, Hao W, Chen X, Ma J, Wang B, Shang J, Li D, Zheng Q. Rosmarinic Acid Protects against Inflammation and Cardiomyocyte Apoptosis during Myocardial Ischemia/Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma. Front Pharmacol. 2017 Jul 118:456. doi: 10.3389/fphar.2017.00456. e Collection 2017.
6. Lingling Si, Xinhui Yang, Xinyan Yan, Yanming Wang, Qiusheng Zheng. Isoliquiritigenin induces apoptosis of human bladder cancer T24 cells via the Cyclin-dependent kinases-independent mechanism. Oncology Letters. Published online on:May 12, 2017https://doi.org/10.3892/ol.2017.6159
7. Wang J, Li Y, Yang Y, Chen X, Du J, Zheng Q, Liang Z, Wang Y. A New Strategy for Deleting Animal drugs from Traditional Chinese Medicines based on Modified Yimusake Formula. Sci Rep. 2017 May 47(1):1504. doi: 10.1038/s41598-017-01613-7.
8. Chen XY, Li DF, Han JC, Wang B, Dong ZP, Yu LN, Pan ZH, Qu CJ, Chen Y, Sun SG, Zheng QS. Reprogramming induced by isoliquiritigenin diminishes melanoma cachexia through mTORC2-AKT-GSK3β signaling. Oncotarget. 2017 Mar 29. doi: 10.18632/oncotarget.16655. [Epub ahead of print]
2016
9. Caixia Gao, Xinyan Yan, Bo Wang, Lina Yu, Jichun Han, Defang Li, Qiusheng Zheng: Jolkinolide B induces apoptosis and inhibits tumor growth in mouse melanoma B16F10 cells by altering glycolysis. Scientific Reports 11/2016 2016(6:36114 | DOI: 10.1038/srep36114)., DOI:10.1038/srep36114
10. Lina Yu, Jun Ma, Jichun Han, Bo Wang, Xiaoyu Chen, Caixia Gao, Defang Li, Qiusheng Zheng: Licochalcone B Arrests Cell Cycle Progression and Induces Apoptosis in Human Breast Cancer MCF-7 Cells. Recent Pat Anticancer Drug Discov. 09/2016 11(4)., DOI:10.2174/1574892811666160906091405
11. Shi-Liang Jia, Xue-Ling Wu, Xiao-Xiao Li, Xue-Ling Dai, Zhao-Lan Gao, Zheng Lu, Qiu-Sheng Zheng, Ya-Xuan Sun: Neuroprotective effects of liquiritin on cognitive deficits induced by soluble amyloid-β1-42 oligomers injected into the hippocampus. Journal of Asian natural products research 09/2016 18(12)., DOI:10.1080/10286020.2016.1201811
12. Jichun Han, Defang Li, Xiaoyu Chen, Fanqing Meng, Bo Wang, Xinjie Zhang, Qiusheng Zheng: Effects of Licochalcone A on Cell-cycle Distribution and Glycolysis in Human Bladder Cancer T24 Cells. Journal of food and nutrition research 08/2016 4(8)., DOI:10.12691/jfnr-4-8-9
13. Jichun Han, Defang Li, Xiaoyu Chen, Fanqing Meng, Bo Wang, Xinjie Zhang, Qiusheng Zheng: Hepatoprotective Activities of Huoshan Dendrobium Officinale Kimura et Migo Water Extracts on Carbontetrachloride-induced Hepatotoxicity in Mice.. DOI:10.12691/jfnr-4-8-10
14. Xiaoyu Chen, Ming Yang, Wenjin Hao, Jichun Han, Jun Ma, Caixia Wang, Shiguo Sun, Qiusheng Zheng: Differentiation-inducing and anti-proliferative activities of isoliquiritigenin and all-trans-retinoic acid on B16F0 melanoma cells: Mechanisms profiling by RNA-seq. Gene 07/2016 592(1)., DOI:10.1016/j.gene.2016.07.052
15. Caixia Wang, Wenjuan Xu, Wenjin Hao, Bingsheng Wang, Qiusheng Zheng: Alternol inhibits the proliferation and induces the differentiation of the mouse melanoma B16F0 cell line. Oncology Reports 06/2016 36(2)., DOI:10.3892/or.2016.4844
16. Xinhui Yang, Jiangtao Jiang, Xinyan Yang, Jichun Han, Qiusheng Zheng: Licochalcone A induces T24 bladder cancer cell apoptosis by increasing intracellular calcium levels. Molecular Medicine Reports 05/2016 14(1)., DOI:10.3892/mmr.2016.5334
17. Yanming WANG, Jun MA, Xinyan YAN, Xiaoyu CHEN, Lingling SI, Ying LIU, Jichun HAN, Wenjin HAO, Qiusheng ZHENG: Isoliquiritigenin inhibits proliferation and induces apoptosis via alleviating hypoxia and reducing glycolysis in melanoma B16F10 cells. Recent Patents on Anti-Cancer Drug Discovery 03/2016 11(999)., DOI:10.2174/1573406412666160307151904
18. Wenjuan Wang, Xiaotang Ma, Jichun Han, Mingjie Zhou, Huanhuan Ren, Qunwen Pan, Chunli Zheng, Qiusheng Zheng: Neuroprotective Effect of Scutellarin on Ischemic Cerebral Injury by Down-Regulating the Expression of Angiotensin-Converting Enzyme and AT1 Receptor. PLoS ONE 01/2016 11(1)., DOI:10.1371/journal.pone.0146197
2015
19. Shiliang Jia, Zheng Lu, Zhaolan Gao, Jun An, Xueling Wu, Xiaoxiao Li, Xueling Dai, Qiusheng Zheng, Yaxuan Sun. Chitosan oligosaccharides alleviate cognitive deficits in an amyloid-β1-42-induced rat model of Alzheimer's disease. Int J Biol Macromol. 2016 Feb83:416-25. doi: 10.1016/j.ijbiomac.2015.11.011. Epub 2015 Nov 18.
20. Yun Han, Jun Wu, Tingting Liu, Youdong Hu, Qiusheng Zheng, Binsheng Wang, Haiyan Lin, Xia Li. Separation, characterization and anticancer activities of a sulfated polysaccharide from Undaria pinnatifida. Int J Biol Macromol. 2016 Feb83:42-9. doi: 10.1016/j.ijbiomac.2015.11.049. Epub 2015 Nov 23.
21. Daoxu Qu, Jichun Han, Huanhuan Ren, Wenxiao Yang, Xinjie hang, Qiusheng Zheng, Dong Wang. Cardioprotective Effects of Astragalin against Myocardial Ischemia/Reperfusion Injury in Isolated Rat Heart. Oxidative medicine and cellular longevity, VOLUME 2016 (2016)(ARTICLE ID 8194690,):11 PAGES · DECEMBER 2015
22. Penglong Wang, Xuan Yuan, Yan Wang, Hong Zhao, Xiling Sun, Qiusheng Zheng: Licochalcone C induces apoptosis via B-cell lymphoma 2 family proteins in T24 cells. Molecular Medicine Reports 09/2015 12(5). DOI:10.3892/mmr.2015.4346
23. Xuan Yuan, Hai-tao Niu, Peng-long Wang, Jie Lu, Hong Zhao, Shi-han Liu, Qiu-sheng Zheng, Chang-gui Li: Cardioprotective Effect of Licochalcone D against Myocardial Ischemia/Reperfusion Injury in Langendorff-Perfused Rat Hearts. PLoS ONE 06/2015 10(6):e0128375. DOI:10.1371/journal.pone.0128375
24. Wenjin Hao, Xuan Yuan, Lina Yu, Caixia Gao, Xiling Sun, Dong Wang, Qiusheng Zheng: Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways. Scientific Reports 05/2015 5:10336. DOI:10.1038/srep10336
25. Mingjie Zhou, Liqun Liu, Wenjuan Wang, Jichun Han, Huanhuan Ren, Qiusheng Zheng, Dong Wang: Role of licochalcone C in cardioprotection against ischemia / reperfusion injury of isolated rat heart via antioxidant, anti-inflammatory, and anti-apoptotic activities. Life sciences 04/2015 132. DOI:10.1016/j.lfs.2015.04.008
26. Mingjie Zhou, Huanhuan Ren, Jichun Han, Wenjuan Wang, Qiusheng Zheng, Dong Wang: Protective Effects of Kaempferol against Myocardial Ischemia/Reperfusion Injury in Isolated Rat Heart via Antioxidant Activity and Inhibition of Glycogen Synthase Kinase-3. Oxidative medicine and cellular longevity 03/2015 Article ID 481405(1):1-8. DOI:10.1155/2015/481405
27. Xuejiao Hou, Jichun Han, Changsheng Yuan, Huanhuan Ren, Ya Zhang, Tao Zhang, Lixia Xu, Qiusheng Zheng, Wen Chen: Cardioprotective Effects of Total Flavonoids Extracted from Xinjiang Sprig Rosa rugosa against Acute Ischemia/Reperfusion-Induced Myocardial Injury in Isolated Rat Heart. Cardiovascular toxicology 01/2015 DOI:10.1007/s12012-015-9308-0
28. Ma jun, Yuan Xuan, Qu Hengyi, Zhang juan, Wang dong, Sun Xiling, Zheng Qiusheng: The role of reactive oxygen species in morphine addiction of SH-SY5Y cells. Life sciences 01/2015 124. DOI:10.1016/j.lfs.2015.01.003
2014
29. Caixia Wang, B Zhang, N Chen, Liangliang Liu, Jinglei Liu, Q Wang, Zhenhua Wang, Xiling Sun, Qiusheng Zheng. Alteronol Induces Differentiation of Melanoma B16F0 Cells. Recent Pat Anticancer Drug Discov. 2014 Sep 23. .201510(1):116-27.
30. Jichun Han, Dong Wang,Bacui Yu, YanmingWang, Huanhuan Ren, Bo Zhang, YonghuaWang, Qiusheng Zheng, Cardioprotection against Ischemia/Reperfusion by Licochalcone B in Isolated Rat Hearts. Oxidative Medicine and Cellular Longevity. Volume 2014, Article ID 134862, 11 pages,http://dx.doi.org/10.1155/2014/134862
31. Zhao H1, Yuan X, Jiang J, Wang P, Sun X, Wang D, Zheng Q. Antimetastatic Effects of Licochalcone B on Human Bladder Carcinoma T24 by Inhibition of Matrix Metalloproteinases-9 and NF-кB Activity. Basic Clin Pharmacol Toxicol. 2014 May 26. doi: 10.1111/bcpt.12273.
32. Binsheng Wang, Du Xing, Dong Wang, Qiusheng Zheng, Jun Ma, Sun Xiling, and Hengyi Qu. Protective effects of Elaeagnus angustifolia leaf extract against Myocardial Ischemia/Reperfusion Injury in Isolated Rat Heart. Journal of Chemistry. Volume 2014, Article ID 693573, 6 pages.
33. Wang Z, Wang D, Liu L, Guo D, Yu B, Zhang B, Han B, Sun XL Zheng QS. Alteronol inhibits the invasion and metastasis of B16F10 and B16F1 melanoma cells in vitro and in vivo. Life Sci. 2014 Mar 798(1):31-8. doi: 10.1016/j.lfs.2013.12.213. Epub 2014 Jan 8，
34. Jiang JT, Yuan X, Wang T, Chen T, Zhao H,Yan XY, Wang ZP, Sun XL, Zheng QS*. Antioxidative and Cardio-protective Effects of Total Flavonoids Extracted from Dracocephalum moldavica L., Cardiovascular Toxicology，2014 Jan 7. 01/2014
35. Yuan X, Li T, Xiao E, Zhao H, Li Y, Fu S, Gan L, Wang Z, Zheng Q*, Wang Z. Licochalcone B inhibits growth of bladder cancer cells by arresting cell cycle progression and inducing apoptosis. Food Chem Toxicol. Food Chem Toxicol. 2014 Mar65:242-51. doi: 10.1016/j.fct.2013.12.030. Epub 2013 Dec 31.
36. Liu L, Zhang B, Yuan X, Wang P, Sun X, Zheng QS*. Alternol induces an S-phase arrest of melanoma B16F0 cells. Cell Biol Int. 2014 Mar38(3):374-80. doi: 10.1002/cbin.10226. Epub 2014 Jan 10.
37. Jiang JT, Yuan X, Zhao H, Yan XY, Sun XL, Zheng QS*. Licochalcone A inhibits proliferation of bladder cancer T24 cells by inducing reactive oxygen species production. Biomed Mater Eng. 201424(1):1019-25. doi: 10.3233/BME-130899.
38. Ya-Xuan Sun, Ting Liu, Xue-Ling Dai, Qiu-Sheng Zheng, Bo-Di，Hui & Zhao-Feng Jiang. Treatment with lutein provides neuroprotection in mice subjected to transient cerebral ischemia. Journal of Asian Natural Products Research, 2014,Vol. 00, No. 0, 1–10,
39. Bo Han, Mingming Zhang, Ting Tang, Qiusheng Zheng，Keyu Wang, Le Li, and Wen Chen. The long–term fate and toxicity of PEG–modified single–walled carbon nanotube isoliquiritigenin delivery vehicles in rats. Journal of Nanomaterials Received 28 October 2013 Journal of Nanomaterials. Volume 2014 (2014), Article ID 257391, 8
40. Yaxuan Sun, Ting Liu，Xueling Dai, Zhaofen Jiang, Zhaolan Gao, Mei Zhang, Dong Wang and Qiusheng Zheng*. Neuroprotective Effect of Dracocephalum moldavica L. Total Flavonoids in Transient Cerebral Ischemia in Rats. Annual Research & Review in Biology. 4(12): 1915-1926，2014
2013年
41. Yuan X, Li DF, Zhao H, Jiang JT, Wang PL, Ma XY, Sun XL, Zheng QS*. Licochalcone-A-Induced Human Bladder Cancer T24 Cells Apoptosis Triggered by Mitochondria Dysfunction and Endoplasmic Reticulum Stress. BioMed Research International. Volume 2013, Article ID 474272, 9 pages
42. Yuan X, Yu BC, Wang YM, Jiang JT, Liu LL, Zhao H, Wang Q, Zheng QS*. Involvement of Endoplasmic Reticulum Stress in Isoliquiritigenin-Induced SKOV-3 Cell Apoptosis. Recent Pat Anticancer Drug Discov. 2013 May 18(2):191-9. PubMed PMID: 22963151.
43. Zhao H, Yuan X, Li DF, Chen HM, Jiang JT, Wang ZP, Sun XL, Zheng QS*. Isoliquiritigen Enhances the Antitumour Activity and Decreases the Genotoxic Effect of Cyclophosphamide. Molecules，2013, 18, 8786-8798 doi:10.3390/molecules18088786
44. Chen HM, Zhang B, Yuan X, Yao Y, Zhao H, Sun XL, Zheng QS*. Isoliquiritigenin-induced effects on Nrf2 mediated antioxidant defence in the HL-60 cell monocytic differentiation. Cell Biol Int. 2013 Jul 24. doi: 10.1002/ cbin.10156.
45. Yuan X, Zhang B, Gan L, Wang ZH, Yu BC, Liu LL, Zheng QS*, Wang ZP. Involvement of the Mitochondrion-dependent and the Endoplasmic Reticulum Stress-signaling Pathways in Isoliquiritigenin-induced Apoptosis of HeLa Cell. Biomed Environ Sci. 2013 Apr26(4):268-76. doi: 10.3967/0895-3988.2013.04.005
46. Yu BC, Wang T, Zhang B, Wang ZH, Zheng QS*. Protective Effects of Total Flavonoids from Dracocephalum moldavica L. on Myocardial Ischemia /Reperfusion Injury in the Isolate Rats Heart. J PURE APPL MICROBIO. April 2013. Vol. 7(Spl. Edn,53-57
47. Han B, Zhang MM, Zheng QS, Wang XC, Tang T, Chen W. Sodium Carboxyl Methyl Cellulose for Improvement of the Determination of Polyethylene Glycol Modified Carbon Nanotubes by Raman Spectroscopy. Analytical Letters, 2013 in on page 130624060632006. Other IDs: 10.1080/00032719.2013.800535
48. Penglong Wang, Fang Ran, Jiangtao Jiang, Bo Zhang, Xiling Sun, Qiusheng Zheng, Skikon induced K562 cell apoptosis through oxidative stress. Medical Plant, 2013,4(10):5-8
2012年
49. Chen XY, Zhang B, Yuan X, Yang F, Liu J, Zhao H, Liu LL, Wang YM, Wang ZH, Zheng QS*. Isoliquiritigenin-induced differentiation in mouse melanoma B16F0 cell line. Oxid Med Cell Longev. 20122012:534934. doi: 10.1155/2012/534934. Epub 2012 Dec 10. PubMed PMID: 23304254 PubMed Central PMCID: PMC3529869. IF=3.93
50. Chen HM, Zhang B, Yao Y, Chen N, Chen XY, Tian H, Wang ZH, Zheng QS*. NADPH oxidase-derived reactive oxygen species are involved in the HL-60 cell monocytic differentiation induced by isoliquiritigenin. Molecules. 2012 Nov 1217(11):13424-38. doi: 10.3390/molecules171113424. PubMed PMID: 23147401, IF=2.428
51. Zhang B, Chen N, Chen HM, Wang ZH, Zheng QS*. The critical role of redox homeostasis in shikonin-induced HL-60 cell differentiation via unique modulation of the Nrf2/ARE pathway. Oxid Med Cell Longev. 20122012:781516. doi:10.1155/2012/781516. Epub 2012 Oct 15. PubMed PMID: 23119122 PubMed Central PMCID: PMC3478756.IF=3.93
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1994.7-1998.7煙臺大學(xué)化學(xué)生物理工學(xué)院助教；
1998.7-2002.7煙臺大學(xué)化學(xué)生物理工學(xué)院講師；
2002.7-2004.10 煙臺大學(xué)化學(xué)生物理工學(xué)院副教授；2004年破格晉升教授；
2004.9-2005.4 煙臺大學(xué)海洋學(xué)院藥物研究所所長；
2003.5-2006.5 煙臺綠葉制藥有限責(zé)任公司新藥研發(fā)（兼職）；
2006.7-2013.12新疆特種植物藥資源教育部重點實驗室主任，石河子大學(xué)藥學(xué)院副院長。
2014.01至今 濱州醫(yī)學(xué)院中西醫(yī)結(jié)合學(xué)院院長。

[教育背景]
1987.9-1991.6 蘭州大學(xué)生物系動物學(xué)專業(yè)學(xué)習(xí)，同年推薦免試碩士研究生；
1991.9.-1994.6 蘭州大學(xué)生物物理專業(yè)學(xué)習(xí)，獲理學(xué)碩士學(xué)位；
2000.9-2003.6 蘭州大學(xué)細胞生物學(xué)專業(yè)學(xué)習(xí)，獲理學(xué)博士學(xué)位；
2005.5-2008.9 北京大學(xué)天然藥物與仿生藥物國家重點實驗室博士后流動站工作。 以上老師的信息來源于學(xué)校網(wǎng)站，如有更新或錯誤，請聯(lián)系我們進行更新或刪除，聯(lián)系方式

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