姓　　名： 劉寶 性別： 男

出生年月： 1962-11-26 工作單位： 東北師范大學(xué)

所在院系： 生命科學(xué)學(xué)院 職稱(chēng)： 教授

行政職務(wù)： 招生專(zhuān)業(yè)： 071001植物學(xué)

研究領(lǐng)域： 植物遺傳學(xué)基礎(chǔ)和應(yīng)用 是否兼職： 否

指導(dǎo)博士生總數(shù)： 指導(dǎo)碩士生總數(shù)：

目前博士生數(shù)： 目前碩士生數(shù)：

個(gè)人簡(jiǎn)介

【個(gè)人情況綜述】 　　1992年畢業(yè)于南京農(nóng)業(yè)大學(xué)獲博士學(xué)位；1995-1997，在以色列Weizmann Institute of Science植物科學(xué)系從事博士后研究；2000-2001，在美國(guó)Iowa State University生態(tài)與進(jìn)化系做訪問(wèn)學(xué)者。 　　主要從事植物基因組進(jìn)化和利用遠(yuǎn)緣雜交及生物技術(shù)進(jìn)行作物遺傳改良的研究。 在植物異源多倍體基因組進(jìn)化和利用野生稻（菰, Zizania latifolia）改良水稻等方面取得多項(xiàng)成果。 發(fā)表研究論文60余篇，其中50余篇發(fā)表在本領(lǐng)域國(guó)際雜志（SCI）上。研究成果受到國(guó)際權(quán)威的認(rèn)可和好評(píng)，多篇論文已被國(guó)際同行廣泛引用。據(jù)不完全統(tǒng)計(jì)，從1998年至今被SCI雜志他人引用超過(guò)500次， 包括被Nature Genetics, Nature Biotechnology, The EMBO Journal, , PNAS, Trends in Genetics, The Plant Cell等國(guó)際權(quán)威雜志的多次引用和評(píng)述。自1999年以來(lái)分別應(yīng)邀為Genetics, Plant Physiology, Plant Molecular Biology, Theoretical and Applied Genetics, Genome, Genetica 等多家本領(lǐng)域國(guó)際雜志評(píng)審論文。 2次被國(guó)際雜志Current Genomics 和Molecular Phylogenetics and Evolution 約稿撰寫(xiě)綜述。 　　應(yīng)用研究方面作為主要合作者，通過(guò)生物技術(shù)與傳統(tǒng)育種相結(jié)合，培育出6個(gè)作物新品種，并參加了其推廣工作。其中水稻新品種“通35號(hào)”連續(xù)多年占吉林省水稻種植總面積的50％以上，已累計(jì)增產(chǎn)稻谷超過(guò)30億公斤。應(yīng)用成果獲得5項(xiàng)省級(jí)科技獎(jiǎng)勵(lì)。 　　至今已負(fù)責(zé)并完成多項(xiàng)國(guó)家和地方政府支持的基礎(chǔ)課題的研究工作。目前正在承擔(dān) “國(guó)家杰出青年科學(xué)基金”、“國(guó)家自然科學(xué)基金重點(diǎn)項(xiàng)目”和國(guó)家科技部“973項(xiàng)目”（子課題）等課題的研究工作。 　　【學(xué)習(xí)工作簡(jiǎn)歷】 　　主要學(xué)習(xí)簡(jiǎn)歷 　　1981-1985，吉林農(nóng)業(yè)大學(xué)農(nóng)學(xué)系，本科，獲學(xué)士學(xué)位。 　　1985-1988，吉林農(nóng)業(yè)大學(xué)農(nóng)學(xué)系，研究生，獲碩士學(xué)位。 　　1989-1992，南京農(nóng)業(yè)大學(xué)細(xì)胞遺傳研究所，研究生，獲博士學(xué)位。 　　1992-1994，東北師范大學(xué)遺傳與細(xì)胞研究所，博士后研究人員。 　　1995-1997，以色列Weizmann Institute of Science植物科學(xué)系，博士后研究人員。 　　2000-2001，美國(guó)Iowa State University, 生態(tài)與進(jìn)化系，訪問(wèn)學(xué)者。 　　主要工作簡(jiǎn)歷 　　1992-1994，東北師范大學(xué)遺傳與細(xì)胞研究所，博士后研究人員。 　　1998－2003，東北師范大學(xué)遺傳與細(xì)胞研究所，教授、博士生導(dǎo)師。 　　2003-至今，東北師范大學(xué)植物分子表觀遺傳學(xué)實(shí)驗(yàn)室，主任、教授、博士生導(dǎo)師。 　　【社會(huì)學(xué)術(shù)兼職】 　　1．“國(guó)家基金委”生命學(xué)部二審專(zhuān)家 　　2．“全國(guó)科技名詞審定委員會(huì)” 委員 　　3．“吉林省遺傳學(xué)會(huì)” 理事

獲得獎(jiǎng)項(xiàng)

應(yīng)用研究成果獲得5項(xiàng)省級(jí)科技獎(jiǎng)勵(lì)。

著作及論文

發(fā)表的主要論文 (*為通訊作者)： 　　1.Yu Chen, Likun Long, Xiuyun Lin, Wanli Guo and Bao Liu*. (2006) Isolation and characterization of a set of disease resistance gene analogs (RGAs) from wild rice, Zizania latifolia Griseb.I. introgression, copy number liability, sequence change and DNA methylation alteration in several rice-Zizania introgression lines. Genome (in press). 　　2.Wanli Guo, Yidan Li, Lei Gong, Fengxia Li, Yingshan Dong & Bao Liu*. (2006). Efficient micropropagation of Robinia ambigua var. idahoensis (Idaho Locust) and detection of genomic variation by ISSR markers. Plant Cell, Tissue and Organ Culture (in press). 　　3.W. L. Guo,　L. Gong,　Z. F. Ding,　Y. D. Li,　F. X. Li,　Y. P. Zhao and　B. Liu*. (2006) Genomic instability in phenotypically normal regenerants of medicinal plant Codonopsis lanceolata Benth. et Hook. f., as revealed by ISSR and RAPD markers. Plant Cell Reports (in press). 　　4.Long L, Lin X, Zhai J, Kou H, Yang W, Liu B*. (2006) Heritable alteration in DNA methylation pattern occurred specifically at mobile elements in rice plants following hydrostatic pressurization. 　　Biochem Biophys Res Commun. 340: 369-376. 　　5.Yong-Ming Wang, Zhen-Ying Dong, Zhong-Juan Zhang, Xiu-Yun Lin, Ye Shen, Daowei Zhou and　 Bao Liu*. (2005) Extensive de novo Genomic Variation in Rice Induced by Introgression from Wild Rice (Zizania latifolia Griseb.) Genetics, 170: 1945-1956. 　　6.Fangpu Han, George Fedak, Wanli Guo, and Bao Liu*. (2005) Rapid And Repeatable Elimination of a Parental Genome-Specific DNA Repeat (pGc1R-1a) in Newly Synthesized Wheat Allopolyploids Genetics, 170: 11239-1245. 　　7.Xiaohui Shan, Zhenlan Liu, Zhenying Dong, Yongming Wang, Yu Chen, Xiuyun Lin, Likun Long, Fangpu Han, Yingshan Dong and Bao Liu*. (2005) Mobilization of the Active MITE Transposons mPing and Pong in Rice by Introgression from Wild Rice (Zizania latifolia Griseb.) Molecular Biology and Evolution 22: 976-990. 　　8.Y. Z. Dong, Z. L. Liu, X. H. Shan, T. Qiu, M. Y. He and Bao Liu*. (2005) Allopolyploidy in Wheat Induces Rapid and Heritable Alterations in DNA Methylation Patterns of Cellular Genes and Mobile Elements. Genetike, 41: 1089-1095. 　　9.Ye Shen, Xiuyun Lin, Xiaohui Shan, Chunjing Lin, Fangpu Han, Jinsong Pang and Bao Liu*. (2005) Extensive Genomic Rearrangement in Endogenous Long Terminal Repeat (LTR) Retrotransposons of Rice Lines Introgressed by Wild Rice, Zizania Latifolia Griseb. Journal of Integrative Plant Biology, 47: 998-1008 　　10.Fangpu Han, Bao Liu, George Fedakand Zhaohui Liu. (2004) Genomic constitution and variation in five partial amphiploids of wheat-Thinopyrum intermedium as revealed by GISH, multicolor GISH and seed storage protein analysis. Theoretical and Applied Genetics, 109: 1070-1076. 　　11.Zhenlan Liu, Yongming Wang, Ye Shen, Wanli Guo, Shui Hao, and Bao Liu*. (2004) Extensive alterations in DNA methylation and transcription in rice caused by introgression from Zizania latifolia Plant Molecular Biology, 54: 571-582. 　　12.Z.L. Liu, F.P. Han, M. Tan, X.H. Shan, Y.Z. Dong, X.Z. Wang, G. Fedak, S. Hao, Bao Liu*. (2004) Activation of a rice endogenous retrotransposon Tos17 in tissue culture is accompanied by cytosine demethylation, and causes heritable alteration in methylation pattern of flanking genomic regions. Theoretical and Applied Genetics, 109: 200-209. 　　13.Dong YS, Zhao LM, Liu Bao, Wang ZW, Jin ZQ, Sun H. (2004) The genetic diversity of cultivated soybean grown in China. Theoretical and Applied Genetics 108: 931-936. 　　14.Wang Y, Lin X, Dong B, Wang Y, Liu B. 2004. DNA methylation polymorphism in a set of elite rice cultivars and its possible contribution to inter-cultivar differential gene expression.　Cell Mol Biol Lett. 9: 543-556. 　　15.Yingshan Dong, Xiuling Bu, Yushi Luan, Mengyuan He and Bao Liu*. (2004) Molecular characterization of a cryptic wheat- Thinopyrum intermedium translocation line: evidence for genomic instability in nascent allopolyploid and aneuploid lines. Genetics and Molecular Biology, 27: 237-241. 　　16.Bao Liu & Jonathan F. Wendel. (2003) Epigenetic phenomena and genome evolution in allopolyploid plants. Molecular Phylogenetics & Evolution 29: 365-379. 　　17.Bao Liu, G. Segal, J. K. Rong and M. Feldman. (2003) Characterization of a chromosome-specific sequence in genome B of common wheat implies its origin from Aegilops searsii. Plant Systmatics & Evolution 241: 55-66. 　　18.F. P. Han, G. Fedak, T. Quellet and Bao Liu. (2003) Rapid genomic changes in interspecific and intergeneric hybrids and allopolyploids of Triticeae. Genome 46：716-723. 　　19.David S. Senchina1, Ines Alvarez1, Richard C. Cronn, Bao Liu, Junkang Rong, Richard D. Noyes, Andrew H. Paterson, Rod A. Wing, Thea A. Wilkins, and Jonathan F. Wendel. (2003) Rate variation among nuclear genes and the age of polyploidy in Gossypium. Molecular Biology & Evolution 20: 633-643. 　　20.Bao Liu & Jonathan F. Wendel. (2002) Non-Mendelian phenomena in polyploid genome evolution. Current Genomics 3: 489-506. 　　21. Jonathan F. Wendel, Richard C. Cronn, Ines Alvarez, Bao Liu, Randall L. Small and David S. Senchina. (2002) Intron Size and Genome Size in Plants. Molecular Biology & Evolution 19: 2346–2352. 　　22.Bao Liu, CL Brubaker, G Mergeai, RC Cronn & JF Wendel. (2001) Polyploid formation in cotton is not accompanied by rapid genomic changes. Genome 44: 321-330. 　　23.Bao Liu & Jonathan F. Wendel. 2001. Inter-simple sequence repeat (ISSR) polymorphisms as a genetic marker system in cotton. Molecular Ecology Notes 3: 205-208. 　　24.Bao Liu*, Zhenlan Liu, Yuzhu Dong, Jihong Zhao, Baiqu Huang & Mengyuan He. 2001. Cytosine methylation changes in rice centromeric and telomeric sequences induced by foreign DNA introgression. Biologia Plantarum 44: 203-206. 　　25.Bao Liu*, Yushi Luan, Fangpu Han, Wanquan Ji & Mengyuan He. 2001. Cell culture induced introgression of Thinopyrum intermedium chromatin into common wheat. Plant Cell, Tissue & Organ Culture 65: 9-13. 　　26.Bao Liu & Jonathan F. Wendel. (2000) Retrotransposon activation followed by rapid repression in introgressed rice plants. Genome 43: 874-880. 　　27.Ueng PP, A Hang, H Tsang, JM Vega, L Wang, CS Burton, FT He & Bao Liu. (2000) Molecular analyses of a repetitive DNA sequence in wheat (Triticum aestivum L.). Genome 43: 556-563. 　　28.Bao Liu*, ZL Liu and XW Li. (1999) Production of a highly asymmetric somatic hybrid between rice and Zizania latifolia: evidence for inter-genomic exchange. Theoretical and Applied Genetics 98: 1099-1103 . 　　29.Bao Liu, Hengmao Piao, Fenshan Zhao, Jihong Zhao, Zhenlan Liu & Baiqu Huang. (1999) DNA methylation changes in rice induced by Zizania latifolia (Griseb.) DNA introgression. Hereditas 131: 75-78. 　　30.Bao Liu, JM Vega, M Feldman. (1998) Rapid genomic changes in newly synthesized amphiploids of Triticum and Aegilops. II. changes in low-copy coding DNA sequences. Genome 41: 535-542. 　　31.Bao Liu, JM Vega, G Segal, S Abbo, M Rodova, M Feldman. (1998) Rapid genomic changes in newly synthesized amphiploids of Triticum and Aegilops. I. changes in low-copy noncoding DNA sequences. Genome 41: 272-277. 　　32.Bao Liu, G Segal, JM Vega, M Feldman & S Abbo. (1997) Isolation and characterization of chromosome-specific DNA sequences from a chromosome arm-specific library of common wheat. The Plant Journal 11: 959-965. 　　33.Moshe Feldman, Bao Liu, Gregorio Segal, Shahal Abbo and June M. Vega. (1997) Rapid elimination of low-copy DNA sequences in polyploid wheat: a possible mechanism for differentiation of homoeologous chromosomes. Genetics 147: 1381-1387. 　　34.Segal G, Bao Liu, J.M Vega, S Abbo & M Feldman. (1997) Identification of a chromosome-specific probe that maps within the Ph1 deletion in common and durum wheat. Theoretical and Applied Genetics 94: 968-970. 　　35.Tao Wenjing, Liu Bao* & Xing Miao. (1997) Estabilishing japonica rice suspensions retaining a high regeneration potential after 14 months of culture. Plant Cell, Tissue and Organ Culture 47: 213-216. 　　專(zhuān)利等實(shí)用成果： 　　負(fù)責(zé)或參加的項(xiàng)目成果有近10項(xiàng)通過(guò)省級(jí)或省級(jí)以上鑒定。

承擔(dān)項(xiàng)目

（在研項(xiàng)目） 　?。?） 高等植物遠(yuǎn)緣雜交誘導(dǎo)的表觀遺傳變異及其在物種進(jìn)化和新種形成中的可能作用“國(guó)家自然科學(xué)基金” 重點(diǎn)項(xiàng)目， 2005－2008，負(fù)責(zé)。 　?。?） 水稻重要農(nóng)藝性狀的比較基因組研究（編號(hào)：2005CB120805）。2006－2010，參加人。 　?。?） 大豆抗食心蟲(chóng)、高蛋白、高油、抗蚜蟲(chóng)分子標(biāo)記及新品種選育?！翱萍疾?63計(jì)劃” 2004－2006，負(fù)責(zé)（第二位）。 　?。?） 菰DNA漸滲誘導(dǎo)水稻表觀遺傳變異及其與表型變異的關(guān)系?！皣?guó)家自然科學(xué)基金”， 2004.1－2006.12，負(fù)責(zé)。 　　（5） 高等植物異源多倍體物種形成和基因組進(jìn)化的機(jī)制和規(guī)律研究 “國(guó)家杰出青年科學(xué)基金”,　2003.1－2006.12， 負(fù)責(zé) 　?。?） 菰DNA漸滲誘導(dǎo)水稻遺傳變異的機(jī)理研究“吉林省杰出青年科學(xué)研究計(jì)劃”（2002-2005），負(fù)責(zé)